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The outcome of liver infection by hepatitis C virus in kidney failure patients who undergo kidney transplantation

The Impact of Hepatitis C Virus Infection on the Clinical Course , Short Term and Long-Term Outcome in Renal Transplant Recipients â?? A Prospective and Retrospective Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2015/02/005513
Enrollment
60
Registered
2015-02-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- HEPATITIS C POSITIVE PATIENTS UNDERGOING RENAL TRANSPLANTATION

Interventions

Intervention1: NOT APPLICABLE: THIS IS AN OBSERVATIONAL STUDY WHERE HCV POSITIVE RENAL FAILURE PATIENTS WILL BE COMPARED WITH HCV NEGATIVE RENAL FAILURE PATIENTS WHO UNDER RENAL TRANSPLANTATION Contro

Sponsors

RABINDRANATH TAGORE INTERNATIONAL INSTITUTE OF CARDIAC SCIENCESKOLKATA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. AGE: No age bar for transplantation. 2. SEX: Both males and females are to be selected for the study. 3. Patients with ESRD having hepatitis C virus infection. 4. Patient or family member must give informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who are positive for Human Immuno-deficiency virus (HIV) or Hepatitis B virus infection (HBsAg). 2. Informed consent not given by patient or family member.

Design outcomes

Secondary

MeasureTime frame
1.liver histology post renal transplant. 2.mortality due to other causes 3.number of hospital addmission post transplantTimepoint: retrospective 7 years prospective 2 years—

Primary

MeasureTime frame
1.Acute rejection- when serum creatinine level increases by more than 30% of basal values. 2.Graft loss-defined as return of the patient to dialysis or patient death. 3.Post-operative liver function 4.HCV RNA-by quantitative polymerase chain reaction (PCR) assays Timepoint: SERUM CREATININE AT 1, 3, 6, 12 MONTHS LIVER FUNCTION TEST AT 1,3 6,12 MONTHS LIPID PROFILE AT 1,3, 6,12 MONTHS DEATH OR RETURN TO DIALYSIS ANY TIME DURING THE STUDY PERIOD—

Countries

Bangladesh, Bhutan, Cambodia, Ethiopia, India, Indonesia, Nepal, Nigeria, Philippines

Contacts

Public ContactDr Rohit Rungta

RABINDRANATH TAGORE INTERNATIONAL INSTITUTE OF CARDIAC SCIENCE, KOLKATA

deptnephro@gmail.com919831824751

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026