Health Condition 1: null- Pathologically (histologically or cytologically) confirmed diagnosis of solid tumor (breast, lung, colorectal and head and neck)
Conditions
Interventions
Intervention1: Biopsy: The biopsy tissue will be processed to obtain the primary cell line. In the next stage of the study, the cultured primary cell line will be subjected to
various chemotherapeutic
Sponsors
Jehangir Clinical Development Centre Pvt Ltd
Eligibility
Inclusion criteria
Inclusion criteria: 1. Males and females above 18 years of age. 2. Pathologically (histologically or cytologically) confirmed diagnosis of solid tumor. 3. Tumor must be amenable to biopsy. 4. Must be willing to participate and has signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Other active malignancy except non-melanoma skin cancer, in situ carcinoma of the cervix, or prostate cancer within the no current biochemical (PSA) or radiologic evidence of disease 2. Patients with known or symptoms suggesting brain metastases. 3. Distant metastatic disease. 4. Known HIV-positive patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To validate methodology to establish primary tumor cell line from biopsy samples of cancer patients like breast cancer, NSCLC, Head & Neck, Colorectal.Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| To validate maintenance of isolated primary tumor cells in the laboratory and cryopreserve for development of gene expression panel, microarray profiling and protein expression.Timepoint: After primary cell line culture | — |
Countries
India
Contacts
Public ContactDr Rajesh Savkur
Jehangir Clinical Development Centre Pvt Ltd
Outcome results
None listed