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effect of two drugs on blood pressure,heart rate and eye pressure during laparoscopic surgery of gall bladder

â??HAEMODYNAMIC AND INTRAOCULAR PRESSURE EFFECT OF CLONIDINE AND NITROGLYCERINE INFUSION IN LAPAROSCOPIC CHOLECYSTECTOMYâ??

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/01/005434
Enrollment
60
Registered
2015-01-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients with gall bladder disease

Interventions

Intervention1: clonidine: intravenous infusion @ 1.5 microgram per kg body weight per hour starting after induction of pneumoperitoneum till end of anaesthesia Control Intervention1: nitroglycerine: i

Sponsors

Indira Gandhi Institute of Medical Sciences patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade 1 and 2 2. patients scheduled for laparoscopic cholecystectomy 3. patients willing to give consent

Exclusion criteria

Exclusion criteria: 1. history of allergy to treatment drugs 2. history of hypertension, ischaemic heart disease, valvular heart disease, diabetes, glaucoma. 3. ASA grade 3 and 4 4. patients refusing consent

Design outcomes

Primary

MeasureTime frame
1. heart rate 2. mean blood pressure 3. intraocular pressure Timepoint: 0,5,10,15,20,25,30,35,40,45,50,55,60,65 minutes—

Secondary

MeasureTime frame
1. hypotension 2. bradycardiaTimepoint: 0,5,10,15,20,25,30,35,40,45,50,55,60,65 minutes—

Countries

India

Contacts

Public ContactPrakash Kumar Dubey

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCE

pkdubey@hotmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026