Health Condition 1: null- American Society of Anaesthesiologists Physical Status 1 or 2
Conditions
Interventions
Intervention1: Group BDexB
: receives dexmedetomidine 1 ug/kg rounded to the nearest 10 ug in 20 ml 0.9 % NaCl first 10 mins, followed by spinal anaesthesia and then 20 ml 0.9 % NaCl over next 60 mins
Sponsors
Manipal University
Eligibility
Inclusion criteria
Inclusion criteria: patients undergoing elective infraumbilical or lower limb surgery in the supine position under spinal anaesthesia belonging to american society of anaesthesiologists physical status 1 or 2.
Exclusion criteria
Exclusion criteria: Patients who do not consent for subarachnoid anaesthesia Patients with coagulopathy, hypovolaemia, BMI > 35 kg/m2, spinal abnormalities Chronic use of sedatives or antidepressants History of regular alcohol consumption Local infection over lumbar spine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| onset of analgesia at T10. highest level of analgesia. 2 segment regression. recovery at S2-3. onset of motor block and recovery . sedation score.Timepoint: onset of analgesia at T10.sensory level then checked every 2 mins till highest level of analgesia achieved then every 5 mins till end of 1 hr and every 15 mins till 2 segment regression, recovery. time of recovery at S2-3. motor blockade assessed using modified bromage score.onset time is when bromage score of 3 is obtained and motor recovery when modified score is 0. sedation score.sedation score recorded using ramsay sedation score every 15 mins throughout first 3 hrs. | — |
Secondary
| Measure | Time frame |
|---|---|
| haemodynamic parameters-blood pressure, heart rate, saturation. other side effects like nausea, vomiting or pruritusTimepoint: BP and heart rate every 2.5 mins for first 15 mins.then 5 mins for first hour and then every 15 mins till complete recovery. | — |
Countries
India
Contacts
Public ContactKavya R Upadhya
Kasturba Medical College, Manipal
Outcome results
None listed