Health Condition 1: null- aSAH Patients with ASA 1,2or3 with Hunt & Hess grade 1,2 or 3 with WFNS grade 1,2 or3
Conditions
Interventions
Intervention1: PROPOFOL AS MAINTENANCE AGENT: PROPOFOL AS INTRAVENOUS ANAESTHETIC AGENT given as continous infusion with targeted depth of anaesthesia measured by BIS index (value 40-60)
Control Inter
Sponsors
PGIMER CHANDIGARH
NANISH SHARMA
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria (1) Patients scheduled for aSAH surgery with clinical and radiological evidence of cerebral aneurysm. (2) Age between 18 to 65 yrs. (3) H and H grade 1 ,2 & 3 and WFNS grade 1, 2 & 3. (4) ASA 1, ASA 2 and ASA 3 will be included
Exclusion criteria
Exclusion criteria: Exclusion Criteria (1) Patients with systemic disease other than hypertension and diabetes mellitus. (2) Patients with infectious diseases and respiratory complications. (3) Duration of anesthesia more than six hours. (4) Second operation. (5) Low level of education. (6) Patients with known psychiatric disease. (7) Cardiovascular disease and respiratory impairment. (8) History of drug abuse. (9) Known allergy to any of the anesthetic agent to be used in study. (10) Patients who are unconscious, intubated or tracheostomised even after two weeks following exposure to anesthesia will also be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparision of POCD between study group desflurane and propofol postoperativelyTimepoint: MOCA score 0 to 30 | — |
Secondary
| Measure | Time frame |
|---|---|
| comparision of haemodynamics and brain bulge between study groups desflurane and propofol intraoperativelyTimepoint: brain bulge score 0 to4 | — |
Countries
India
Contacts
Public ContactNANISH SHARMA
PGIMER
Outcome results
None listed