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Prevention of pain due to propofol (used for induction of anesthesia) injection: A comparative study of lignocaine ( used for local anaesthetic action) and dexmedetomidine ( used to decrease pain of injection) and control group

Prevention of pain due to propofol injection: A comparative study of lignocaine, dexmedetomidine and placebo.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/01/005424
Enrollment
90
Registered
2015-01-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA I & II undergoing surgery under general anaesthesia

Interventions

Intervention1: dexmedtomidine: alpha 2 agonist dose: 0.25microgram /kg injected once over 5 secs intravenously Control Intervention1: Lignoacine, Dexmedtomidine , Normal saline: ligocaine: local anaes

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Written informed consent. Patients of either sex. Aged between 17 -70 years Belonging to ASA GRADE 1 and 2( Based on the physical status,the patients are classified into categories by American Society of Anaesthesiologists) Requiring standard General Anaesthesia (G.A)

Exclusion criteria

Exclusion criteria: Concomitant analgesic or sedative medication, patients requiring rapid sequence induction, anticipated difficulty venous access, difficulty in communication Known sensitivity to lignocaine or dexmedetomidine Conditions where use of lignocaine and dexmedetomidine may be harmful Presence of infection on the dorsum of hand

Design outcomes

Primary

MeasureTime frame
Incidence and severity of pain due to propofol injection. Effect of lignocaine, dexmedetomidine and placebo prtreatment in attenuating this pain.Timepoint: AT the time of induction of anesthesia.

Secondary

MeasureTime frame
To assess the recall of pain in patients after the surgery.Timepoint: In the recovery room after the surgery

Countries

India

Contacts

Public ContactSnigdha

Indira Gandhi Institute of Medical Sciences,Patna

patnaarun@yahoo.com9431044957

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026