Health Condition 1: null- Childhood Asthma
Conditions
Interventions
Intervention1: Montelukast in syrup: 10mg at 0hr and 24 hr for age below 12 yrs
20mg at 0 hr and 24 hr for age above12 yrs
Control Intervention1: Placebo-syrup base identical in colour,taste and volum
Sponsors
Fluid research FundChristian Medical college
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 5-15 completed years with a diagnosis of asthma presenting with mild to moderate acute exacerbation (modified pulmonary index score 5-11)
Exclusion criteria
Exclusion criteria: 1.Severe exacerbations with a modified pulmonary index score >12. 2.Children who have been already started on oral steroids for present exacerbation 3.Children on treatment with daily monteleukast in the last month 4.Children who cannot remain in hospital for atleast 4 hours from the onset of treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified pulmonary index score 4 hours after study drug.Reduction in score will be compared with placebo armTimepoint: Modified Pulmonary Index Score(MPIS)measured at 0 hour and 4 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in peak expiratory flow rateTimepoint: from baseline to 4 hours and 36 -48 hours;need for steroid useTimepoint: 4 hours and 36-49 hours;subjective improvement of symptoms using visual analog scaleTimepoint: from baseline to 4 hours and 36 -48 | — |
Countries
India
Contacts
Public ContactDr C Rahul Reddy
Christian Medical College, Vellore
Outcome results
None listed