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effect of epidural steroid injection on body steroid levels

THE EFFECT OF EPIDURAL STEROID INJECTIONS ON HYPOTHALAMIC PITUITARY ADRENOCORTICAL AXIS IN LOW BACK PAIN WITH RADICULOPATHY

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/01/005383
Enrollment
30
Registered
2015-01-12
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic Low back pain with radicular pain

Interventions

Intervention1: ESI: Patients will receive 80 mg of methylprednisolone acetate through epidural route Control Intervention1: not applicable: not applicable

Sponsors

Post Graduate Institute of Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Chronic low-back with lumbosacral radilcular pain patients 2. Having pain for at least 1 month 3. With pain score of more than 5 on Visual Analogue scale

Exclusion criteria

Exclusion criteria: coagulopathy, infection at the procedure site, allergy to corticosteroids, pregnancy, all endocrinology diseases, history of corticosteroid treatment in the preceding year, desi medications, chronic medical illnesses (diabetes, hypertension, heart failure, renal disease, liver disease, etc.), sleep disturbance, taking contraceptives, severe stress in the preceding month, those working at night shifts and grossly obese patients

Design outcomes

Primary

MeasureTime frame
Plasma Cortisol and ACTH levelsTimepoint: Plasma Cortisol and ACTH levels

Secondary

MeasureTime frame
1. Overall NRS 2. Overall MODQ Timepoint: Baseline, 0.5 and 1 month

Countries

India

Contacts

Public ContactBabita Ghai

Post Graduate Institute of Medical Education and Research

ghaibabita1@gmail.com7087009533

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026