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A clinical trial to study the changes in biomarkers of saliva and blood in males with alcohol dependence syndrome, before and after deaddiction treatment.

Salivary Proteins and Enzyme markers of Alcoholism : A Comparative and Correlative Study of Carbohydrate-Deficient Transferrin, Exoglycosidases, Liver Function Marker Enzymes and Protein-Bound Sialic acid in Alcohol dependent males .

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2015/01/005372
Enrollment
114
Registered
2015-01-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Alcohol Dependence syndrome

Interventions

None listed

Sponsors

Father muller medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Males in the age group of 18-65 years 2) Group I : diagnosed of alcohol dependence by the treating psychiatrist, based on The ICD-10 (the 10th revision of the International Statistical Classification of Diseases ) Classification of Mental and Behavioural Disorders : Diagnostic Criteria for research of WHO .1,2 currently using substance and smokers 3) Group II : diagnosed of alcohol dependence by the treating psychiatrist, based on The ICD-10, DCR of WHO .1,2 currently using substance and non-smokers. 4) Group I(a) & Group II (a) : diagnosed of alcohol dependence by the treating psychiatrist, based on The ICD-10, DCR of WHO .1,2 currently abstinence, smokers and non-smokers, respectively. 5) Group III : Age matched, apparently healthy non-alcoholic, non smoker male volunteers

Exclusion criteria

Exclusion criteria: 1) Age : 65 years.(all groups) 2) Use of substances (control group) 3) Systemic illness: Non alcoholic liver disease, kidney disease, cancer, inflammatory diseases, infections, etc.(all groups) 4) Lost for follow up or those who withdrew from study(all groups)

Design outcomes

Primary

MeasureTime frame
Salivary biochemical parameters as biomarkers of alcohol dependence.Timepoint: Salivary biochemical parameters as biomarkers of alcohol dependence.

Secondary

MeasureTime frame
Alcohol deaddiction will ameliorate the salivary biochemical parametersTimepoint: 30 days

Countries

India

Contacts

Public ContactDr Shivashankara AR

Father Muller Medical College

arshiva72@gmail.com9880146133

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026