Health Condition 1: null- Heart failure with reduced ejection fraction
Conditions
Interventions
None listed
Sponsors
Prof Dr CG Bahuleyan MDDM FRCP FSCAI
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female patients above 18 years of age. 2. Patients with at least one of the following clinical symptoms of HF a) dyspnea b) orthopnea c) paroxysmal nocturnal dyspnea d) increasing fatigue / worsening exercise tolerance AND at least two of the following physical signs of heart failure, a) edema (greater than 2 + lower extremity) b) pulmonary crackles greater than basilar c) jugular venous distension d) tachypnea (respiratory rate more than 20 breaths / minutes) e) rapid weight gain f) S3 gallop g) increasing abdominal distension or ascites h) hepatojugular reflux i) radiological evidence of worsening HF 3. Patients with EF 4. Willing to sign informed consent. 5. Expected to be available for follow-up visits.
Exclusion criteria
Exclusion criteria: 1. History of recent ( 2. Severe valvular heart disease. 3. History of recent ( 4. HF due to myocarditis 5. Patients with end stage renal failure (eGFR 6. Acute liver disease ( Alanine transaminase >= 2 times of the upper limit of normal) 7. Patients admitted with cardiogenic shock. 8. Patients with chronic obstructive pulmonary disease (COPD), Interstitial Lung Disease (ILD). 9. Patients undergoing chemotherapy. 10. Any medical condition substantially reducing life expectancy to
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The Primary endpoints are a) Cardiac deaths occurring with in one year follow-up period b) Re-hospitalization for worsening of HF with in one year. 2. The secondary endpoints are a) All cause death with in one year. b) Change in LV function in one year. Timepoint: One year from recruitment | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. The secondary endpoints are a) All cause death with in one year. b) Change in LV function in one year. Timepoint: One year from recruitment | — |
Countries
India
Contacts
Public ContactJinbert Lordson
Ananthapuri Hospitals and Research Institute
Outcome results
None listed