Health Condition 1: null- Chronic Low back pain with or without radicular pain
Conditions
Interventions
Intervention1: Group 80 mg: Patients will receive 80 mg of methylprednisolone acetate through epidural route
Intervention2: Group 80: Patients will receive 80 mg of methylprednisolone acetate through
Sponsors
Department of Science Technology Chandigarh Administration
Eligibility
Inclusion criteria
Inclusion criteria: Chronic low-back pain due to disc prolapse, lumbar spondylosis, and/or spinal stenosis, for at least 3 month refractory to conservative or interventional therapies with pain score of more than 5.
Exclusion criteria
Exclusion criteria: coagulopathy, infection at the procedure site, allergy to corticosteroids, pregnancy, all endocrinology diseases, history of corticosteroid treatment in the preceding year, desi medications, chronic medical illnesses (diabetes, hypertension, heart failure, renal disease, liver disease, etc.), taking contraceptives, severe stress in the preceding month, those working at night shifts and grossly obese patients. None of the subjects consumes alcohol 12 hours before sampling or food one hour before sampling.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma Cortisol and ACTH levelsTimepoint: one, two and four weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Overall VAS 2. Overall MODQ Timepoint: Baseline, 0.5, 1, 2 and 3 months | — |
Countries
India
Contacts
Public ContactBabita Ghai
Post Graduate Institute of Medical Education and Research
Outcome results
None listed