Health Condition 1: null- Vitamin D deficient Adult with prediabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subject who belongs to ï?§ age 30 years up to 60 years ï?§ individuals who met the diabetes risk score criteria ï?§ both male and female ï?§ fasting plasma glucose level 110 to 125 mg/dl ï?§ Oral glucose tolerance test 140 to 199mg/dl. ï?§ vitamin D3 below 30ng/dl
Exclusion criteria
Exclusion criteria: Subjects who with diabetes under medication currently using vitamin D supplements hypercalcaemia above 2.65mmol/l liver disease, Virus or autoimmune hepatitis and cirrhosis history of hyperparathyroidism history of arthritis history of Pulmonary Tuberculosis history of malabsorption Pregnant women History of chronic renal failure, nephrotic syndrome, Renal stone hypothyroidism, and HIV patients on antiviral drugs. History of malignant diseases History of inflammatory diseases
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Vitamin d 3 supplementation Effect on Insulin resistance and Effect on triglyceride Timepoint: Oral supplementation of vitamin D3(Cholecalciferol) 60,000IU/week for 8 weeks followed by 60,000IU/month for 2months to achieve the serum vitamin D 50ng/dl and post test evaluation will be done on 16 th week | — |
Primary
| Measure | Time frame |
|---|---|
| 25 hydroxy vitamin d3 reach 50 or above 50 ng/dl Blood glucose level 80 to 100 mg/dl Timepoint: Oral supplementation of vitamin D3(Cholecalciferol) 60,000IU/week for 8 weeks followed by 60,000IU/month for 2months to achieve the serum vitamin D 50ng/dl and post test evaluation will be done on 16 th week | — |
Countries
India
Contacts
Chettinad Academy of Research and education