Health Condition 1: null- pregnant women with hypertensive emergencies (BP more than 160 and or 110 mm of Hg at more than 24 weeks pregnancy)
Conditions
Interventions
Intervention1: Hydralazine: â?¢ Hydralazine: Intravenous hydralazine will be administered every 20 minutes with till the target BP (150 mm of Hg & diastolic 100 mm of Hg) is achieved in consecutive do
Sponsors
Government of Himachal Pradesh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 18 to 45 years, 2. Period of gestation > 24 weeks of gestation 3. Maternal Heart rate; 60-90 beats per minute 4. Reassuring fetal heart rate.
Exclusion criteria
Exclusion criteria: 1. known case of heart disease (pre-existing angina) 2. Non-pregnancy related hypertension (diagnosed cases of chronic or secondary hypertension) 3. Allergy to either of the drug 4. Need for any acute emergency for cesarean section (Abruptio placentae, severe fetal bradycardia etc)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time required to achieve target systolic BP of 150 mm of Hg or lower and diastolic BP of 100 mm of Hg or lower (both targets had to be fulfilled).Timepoint: 2 hours after delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| ï?? Total number of antihypertensive dosages required to achieve the target BP (systolic BP of 150 mm of Hg or lower and diastolic BP of 100 mm of Hg or lower, both to be fulfilled) ï?? Maternal heart rate profile during the study period ï?? Maternal hypotension (BP less than 90/60 mm Hg) ï?? Side effects profile (Nausea, Vomiting, Headache, dizziness, urticaria, flushing, pruritis, nasal congestion, conjunctivitis, palpitations) ï?? Perinatal outcome Timepoint: 2 hours after delivery | — |
Countries
India
Contacts
Public ContactChanderdeep Sharma
Dr RPGMC Kangra
Outcome results
None listed