Health Condition 1: null- Schizophrenia
Conditions
Interventions
Intervention1: Active repetitive Transcranial Magnetic Stimulation (rTMS): Active continuous theta burst repetitive Transcranial Magnetic Stimulation (rTMS)delivered using Magstim® Rapid2 device (The
Sponsors
Department of Biotechnology Ministry of Science and Technology under INCRE Fellowship
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosis of Schizophrenia (F20.0-F20.9) according to ICD-10-DCR 2. Patients on a stable dose of antipsychotic medication 3. Patients of either sex aged between 18-60 years. 4. Right handed, normotensive patients. 5. Patients giving written informed consent. 6. Screened eligible for rTMS.
Exclusion criteria
Exclusion criteria: 1. Current neurological or any comorbid psychiatric disorders. 2. History of substance abuse (Except nicotine and caffeine) in the past one month. 3. History of epilepsy, significant head injury or any neurosurgical procedure. 4. Subjects with cardiac pacemakers or other metal parts in the body. 5. Subjects who have received ECT in past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Schneiderian First rank symptoms (FRS) assessed with a specially designed score sheetTimepoint: Baseline and at the end of 2 weeks of rTMS treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| high resolution gamma oscillatory activity, BDNF levels, self monitoring task and overall psychopathology scores on PANSSTimepoint: Baseline and at the end of 2 weeks of rTMS treatment | — |
Countries
India
Contacts
Public ContactDr Sai Krishna Tikka
Central Institute of Psychiatry
Outcome results
None listed