To compare the efficacy and safety of amniotic membrane transplantation in acute ocular Stevens-Johnson Syndrome

Prospective Randomised Comparative Study Of Adjuvant Role Of Amniotic Membrane Transplantation In Ocular Manifestations Of Acute Stevens Johnson Syndrome With Standard Therapy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/11/005225

Enrollment

Registered

2014-11-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Acute Stevens-Johnson Syndrome Health Condition 2: L511- Stevens-Johnson syndrome

Interventions

Intervention1: Amniotic Membrane Transplantation: 25 eyes of acute SJS patients with Amniotic Membrane Transplantation along with standard medical therapy Control Intervention1: Standard Medical Ther

Eligibility

Inclusion criteria

Inclusion criteria: acute presentation within 1 month clinical diagnosisby dermatologist no other ocular pathology willing for follow up

Exclusion criteria

Exclusion criteria: prior ocular pathology microbial infection corneal perforation

Design outcomes

Primary

Measure	Time frame
1.maintanance of visual acuity 2.prevention of dry eyeTimepoint: 0 day, 7th day. 30th day, 90th day and 180th day	—

Secondary

Measure	Time frame
prevention of chronic complictions like 1.ectropion 2.entropion 3.symblepharon 4.ankyloblepharon 5.trichiasis 6.distichiasis 7.LSCD 8.corneal haze 9. keratisationTimepoint: 0th day,7th day,30th day. 90th day and 180th day	—

Countries

India

Contacts

Public ContactNamrata Sharma

RPC,AIIMS

arasun.then@gmail.com9958174178

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026