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Effect of antioxidants in vitiligo

ROLE OF ANTI-OXIDANTS ON OXIDATIVE STRESS INDEX IN THE PATIENTS OF VITILIGO

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/11/005223
Enrollment
30
Registered
2014-11-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80- Vitiligo Health Condition 2: null- Vitiligo vulgaris

Interventions

Intervention1: Anti-oxidants like Vitamin C, Vitamin E, Manganese, Selenium, Zinc, Copper, Beta carotene.: Vitamin C 300 mg, Vitamin E 400 IU,Beta carotene 30 mg, Zinc oxide 40 mg, Sodium selenate 200

Sponsors

Shri Ram Murti Smarak Institute of Medical Sciences Bareilly
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Clinically diagnosed case of vitiligo vulgaris • They are not under a therapeutic regimen for previous two months and had not received drugs containing any anti-oxidants • Patient having VIDA score >= +1 • Age >= 18 years • Patients should be willing for Investigation, Treatment and Regular Follow up

Exclusion criteria

Exclusion criteria: • Age • Pregnancy or Lactation at present • Hepatic, Renal, Lipid Profile Abnormalities • Past/Present history of any type of Malignancy • Patient unsure about attending treatment Schedule Regularly • Previous H/o any Hypersensitivity Reaction to anti-oxidants • Patients who fail to come for follow up after Initiation of therapy • Patients with previous H/o Immunobullous disorders nad autoimmune diseases • Patient is an alcoholic and smoker

Design outcomes

Primary

MeasureTime frame
Oxidation stress indexTimepoint: Baseline and after 4 weeks

Secondary

MeasureTime frame
Dermatology life quality indexTimepoint: Baseline and after 4 weeks;Activity and extent of vitiligo with the help of vitiligo disease activity scoreTimepoint: Baseline and after 4 weeks

Countries

India

Contacts

Public ContactDr Pratik Gahalaut

Shri Ram Murti Smarak Institute of Medical Sciences, bareilly

drbradster@gmail.com0581-2582016

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026