Comparison among three different doses of dexmedetomidine for prevention of shivering in patients undergoing turp under spinal anesthesia

Randomised double blind comparative study of three different doses of iv dexmedetomidine for prevention of post spinal anesthesia shivering in patients undergoing transurethral resection of prostate

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/11/005220

Enrollment

150

Registered

2014-11-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients of ASA grade 1 and 2 aged 50-75yrs,undergoing TURP under spinal anesthesia.The drug is being studied for prevention of shivering and for best possible dose.

Interventions

Intervention1: Dexmedetomidine intravenously: Group P -dexmedetomidine given as iv 0.5 microgram/kg bwt. Drug given as iv diluted in 50 ml normal saline given over 10 mins just after spinal anesthesia

Eligibility

Inclusion criteria

Inclusion criteria: Age gr-50 to 75 yrs Patients undergoing TURP ASA 1 and 2 Those willing to give written consent

Exclusion criteria

Exclusion criteria: Allergic to drugs,Contraindications to spinal anesthesia,treatment with alpha blockers,opioids or sedatives use,endocrinal,Cardiopulmonary,hepatic,renal,neurological,psychological disorders,blood transfusion during surgery,initial body temperature >38 or <36C,severe bradycardia or hypotension.

Design outcomes

Primary

Measure	Time frame
To estimate minimum effective dose of intravenous dexmedetomidine to prevent shivering in patients undergoing TURP under spinal anesthesia , to observe other effects like sedation, hypotension, bradycardiaTimepoint: 2 years	—

Secondary

Measure	Time frame
To observe effects like sedation, hypotension, bradycardiaTimepoint: 2years	—

Countries

India

Contacts

Public ContactFahd Hossain

Indira Gandhi Institute of Medical Sciences, Patna

deepakswat@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026