Skip to content

Role of injection phenylephrine in different doses, for the prevention of spinal anaesthesia induced fall of blood pressure on patients of cesarean section.

EFFICACY AND SAFETY OF PROPHYLACTIC DOSES OF IM PHENYLEPHRINE FOR THE PREVENTION OF SPINAL ANAESTHESIA-INDUCED HYPOTENSION IN CESAREAN SECTION

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/11/005218
Enrollment
104
Registered
2014-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Pregnant mothers scheduled to have elective caesarean section under spinal anaesthesia

Interventions

Intervention1: phenylephrine Hydrochloride inj : phenylephrine has alpha-1 agonist action.Its constrict the vessels and increses blood pressure. Group A,B,C were received 1 mg,2 mg and 3 mg IM,and c

Sponsors

soumita roy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: older than 18 years American Society of Anaesthesiologists (ASA) physical status I or II weighing more than 50 kg and less than 90 kg uncomplicated singleton pregnancy beyond 36 weeks, scheduled to have elective caesarean section under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1. Patients not willing to undergo spinal anaesthesia 2. Known hypertensive patients or those with a resting arterial blood pressure >= than 160/90 mm Hg. 3. Known coronary artery disease, cardiac valvular regurgitation and or stenosis. 4. Neuromuscular disorders 5. Patients with history of coagulation disorder 6. Foetal malpresentation 7. Pregnancy -induced hypertension (PIH) 8. History of systemic illness (renal disease, diabetes mellitus etc) 9. Patients on chronic medication

Design outcomes

Primary

MeasureTime frame
ï?? To determine the efficacy of prophylactic doses of IM phenylephrine for the prevention of spinal anaesthesia-induced hypotension in caesarean section.Timepoint: before spinal anaesthesia to 1 hr after caesarean section

Secondary

MeasureTime frame
ï?? To assess the safety of different doses of IM phynylephrine for the prevention of spinal anaesthesia-induced hypotension in caesarean section.Timepoint: before spinal anaesthesia to 1 hr after caesarean section.

Countries

India

Contacts

Public ContactDr Chanchal Kumar Dalai

College of Medicine and JNM Hospital

chanchal.dalai8@gmail.com9474550728

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026