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A Study on Effect of Probiotic Inersan and Doxycycline in Treating Gum Disease

A comparative evaluation of the effect of Probiotic Inersan and Doxycycline on Chronic Periodontitis -A Clinical and Microbiological Study

Status
Recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/11/005215
Enrollment
30
Registered
2014-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with Chronic Periodontitis

Interventions

Intervention1: Inersan: Lactobacillus brevis CD2 1000000000 Colony Forming Units/gm Lozenges Twice daily for 14 days Intervention2: Inersan and Tab. Doxt 100mg: Inersan-Lactobacillus brevis CD2 100000

Sponsors

Sree Mookambika Institute of Dental Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -AAP International Workshop for Classification of Periodontal Diseases,1999. -Subjects of both sexes -Patients in the age group of 25-60 years -Subjects with mild to moderate chronic periodontitis, as defined by probing pocket depths >=5mm in > 30 % of the probing sites. -Subjects in good general health

Exclusion criteria

Exclusion criteria: -Antibiotic therapy in the past 2 months - Allergic to doxycycline or probiotics. -Subjects with diabetic mellitus,hypertension and psychiatric disorders -Subjects who are pregnant/ lactating -Smokers and/or alcoholics. -Those undergone any periodontal therapy within last 6 months.

Design outcomes

Primary

MeasureTime frame
Load of Lacto bacillus will be increased in Probiotic InersanTimepoint: One Month

Secondary

MeasureTime frame
Improvement in clinical outcome and decrease in P. gingivalis count in all three groupsTimepoint: One month

Countries

India

Contacts

Public ContactDr AryaKS

Sree Mookambika Institute of Dental Sciences

elizabethkoshi_dr@yahoo.com9447154335

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026