FindTrial
Sign In

Comparison of different antiemetics for prevention of vomiting after laparoscopic surgery

Comparison of palonosetron 0.075 mg, palonosetron 0.15 mg and palonosetron-dexamethasone combination for prevention of postoperative nausea and vomiting after laparoscopic procedures

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/11/005214
Enrollment
120
Registered
2014-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- undergoing laparoscopic abdominal surgery

Interventions

Intervention1: Palanosetron: 0.15 mg palonosetron administered intravenously before induction of anaesthesia Intervention2: Palanosetron: 0.075 mg palonosetron administered intravenously before induct

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 120 female patients of ASA physical status 1-2 between 19-60 yr of age scheduled to undergo day care laparoscopic gynaecological procedure

Exclusion criteria

Exclusion criteria: Patients with gastrointestinal diseases, smokers, past history of motion sickness, having BMI more than 30 kg/m2

Design outcomes

Primary

MeasureTime frame
the incidence and severity of postoperative nausea and vomitingTimepoint: at 6 hr, 24 hr and 72 hr postoperatively—

Secondary

MeasureTime frame
Requirement of rescue anti emetic and adverse effectsTimepoint: at 6 hr, 24 hr and 72 hr postoperatively—

Countries

India

Contacts

Public ContactNeerja Bharti

PGIMER

bhartineerja@yahoo.com9915575145

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026