Comparision of effect two drug combinations (levobupivacaine with clonidine and ropivacaine with clonidine) on post-surgery pain relief in children (01-06 years) undergoing surgeries below umblicus when drugs are given in space overlying spinal cord.

A prospective double blind comparative clinical study between caudal levobupivacaine (0.125%) with clonidine and ropivacaine (0.125%) with clonidine on post operative analgesia in pediatric patients undergoing infraumblical surgery.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/11/005193

Enrollment

Registered

2014-11-11

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA grade I & II

Interventions

Intervention1: Caudal epidural block: After meeting the inclusion and exclusion criteria the cases (children) selected for study will be divided into two groups (group A and B) by randomisation. The i

Eligibility

Inclusion criteria

Inclusion criteria: •Patients undergoing elective infraumblical surgery with caudal block. •Aged between 01-06 years. •ASA grade 1 & 2. •Those who are willing to give written consent.

Exclusion criteria

Exclusion criteria: •Parental unwillingness •Body weight > 20 kgs •Children with pre existing neurological or spinal disease, cardiovascular,respiratory, renal, hepatic or any other systemic disease •Bleeding diathesis •Infection at the site of block •Abnormalities of the sacrum •Allergic to local anaesthetics •Aspirin ingestion in the preceding week •Chronic use of any anti inflammatory drugs

Design outcomes

Primary

Measure	Time frame
Blood Pressure, heart rate and oxygen saturation.Timepoint: Every 5 minutes intraoperatively and every 15 minutes postoperatively.	—

Secondary

Measure	Time frame
any adverse event.Timepoint: Anytime intraoperatively or postoperatively.	—

Countries

India

Contacts

Public ContactDr Chandrakant Prasad

Indira Gandhi Institute Of Medical Sciences, Patna

drvvinodv@gmail.com9473191825

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026