Health Condition 1: null- All patients with paranasal sinus tumors with potential (close to/involving) dural involvement requiring craniofacial surgery.
Conditions
Interventions
Intervention1: MRI PNS and Brain: MRI done prior to surgery
Control Intervention1: Histopathology: Final histopatholgy
Sponsors
Tata Memorial Centre
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients with paranasal sinus tumors with potential (close to/involving) dural involvement requiring craniofacial surgery. 2. Age > 18 years.
Exclusion criteria
Exclusion criteria: 1. Frank brain invasion, bilateral orbital apex or cavernous sinus involvement. 2. Patients refusing surgery. 3. Patients unfit for surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Diagnostic accuracy of MRI by assessing Sensitivity, Specificity, Positive predictive value, Negative predictive value. a. The endpoint will be pathological evidence of tumor / reactive changes / normal tissue.Timepoint: MRI done prior to surgery will be compared with histology after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| a. Morbidity - CSF leak, meningitis, pneumoencephalus, intracranial hemorrhage, wound infection, neurological deficits. b. Progression free survival, Overall survival Timepoint: 30 day morbidity | — |
Countries
India
Contacts
Public ContactDr Deepa Nair
Tata Memorial Centre
Outcome results
None listed