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Dexmeditomidine will be given intramuscularly 30 minutes before extubation.its effect on post extubation hemodynamics will be studied.Also,sedation and post operative analgesia requirement wiil be studied.It wiil be a double blind placebo controlled trial.

Intramuscular dexmedetomidine 30 minutes before extubation to assess its effect on post-extubation haemodynamics, sedation and analgesic requirements in postoperative period: A double blind placebo controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/11/005167
Enrollment
50
Registered
2014-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: null- post extubation hemodynamic changes and post operative analgesia and sedation requirement

Interventions

Intervention1: dexmeditomidine: Dexmeditomidine will be given intramuscularly in the dose of 2mcg/kg.it will be given as a single dose 30 mintues before extubation. Control Intervention1: normal salin

Sponsors

SGPGIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: all ASA grade 1 patients falling in the above mentioned age group

Exclusion criteria

Exclusion criteria: - Patients with ASA Grade III and IV - Anticipated difficult airway e.g. Mallampati class III,IV - Patients with compromised cardiac, respiratory, renal or hepatic functions - patients receiving regional anaesthesia - Surgery lasting more than 4 hours - Smokers - Blood loss more than 20% of blood volume -Patients requiring postoperative ventilation

Design outcomes

Primary

MeasureTime frame
post extubation hemodynamic changes.Timepoint: 30 minutes after administering intramuscular dexmeditomdine.

Secondary

MeasureTime frame
Sedation and analgesia requirement in the post operative period.Timepoint: 24 hours after administering intramuscular dexmeditomidine.

Countries

India

Contacts

Public ContactDr SP Ambesh

SGPGIMS,Lucknow

madhulika16sep@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026