Health Condition 1: null- Pts of ASA I& II, Female pts undergoing any elective surgery, Age between 25 -65 years, Body Mass Index 30kg/mt2, Hemodynamically stable.
Conditions
Interventions
Intervention1: Estradiol cream: an anesthesiologist not involved in the study will apply estradiol cream to a 10 cm2 area (site of venous cannulation) on the dorsum of the non dominant hand of patient
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Pts of ASA I& II, Female pts undergoing any elective surgery, Age between 25 -65 years, Body Mass Index > 30kg/mt2, Hemodynamically stable,
Exclusion criteria
Exclusion criteria: Pts with a h/o HTN, DM, Liver disease, Renal Failure, peripheral neuropathy, psychiatric disorders. Pts on sedatives, hypnotics, antidepressants, estradiol, analgesic & drugs with effects on the nervous system. Pts allergic to estradiol. Patientâ??s refusal. Abnormal skin condition (broken skin, infection, scar psoriasis, eczema) at the site of VP.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence & severity of Venous cannulation pain and number of first attempt failure.Timepoint: immediatly after venous cannulation. | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of side effects.Timepoint: for 24 hrs | — |
Countries
India
Contacts
Public ContactDr Ghanshyam Yadav
Institute of Medical, Sciences, Banaras Hindu University
Outcome results
None listed