Comparison of two refractive surgery techniques ReLEx SMILE and PRK for the correction of low degrees of short sightedness

Comparison of ReLEx SMILE and PRK in terms of visual and refractive outcomes and patient satisfaction for the correction of low myopia - SMILE VS PRK

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/10/005084

Enrollment

Registered

2014-10-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with low degrees of myopia (Spherical equivalent of -4D)

Interventions

Intervention1: ReLEx SMILE (Refractive Lenticule Extraction, Small Incision Lenticule Extraction): Under topical anaesthesia, VisuMax femtosecond laser (Carl Zeiss Meditec AG) will be used for the sma

the cornea washed with Balanced Salt Solution (BSS). The loose epithelium is then removed as a sheet by lifting the edge of the loosened epithelium with shar

Eligibility

Inclusion criteria

Inclusion criteria: •Myopia with SEQ •Stable corneal conditions within the last 12 months •Stable refraction since past 12 months ( •Healthy ocular surface with stable tear film •Discontinuation of Soft contact lenses 1 week, and rigid contact lenses 3 weeks prior to surgery

Exclusion criteria

Exclusion criteria: •Thin corneas (Corneal pachymetry •Steep corneas Kmax >48 D •Keratoconus suspects or frank keratoconus •Mixed astigmatism •Moderate to severe dry eye (Shirmers1 •Socket / globe /lid anomalies â?? very deep set eyes, nanophthalmos •Severe meibomian gland disease, lid abnormalities •Severe atopy •Contact lens overuse •Pregnant and nursing mother •Autoimmune disorders •Pts on systemic medications eg Iso retinoic acid, hormonal preperations, OCPs, antidepressants.

Design outcomes

Primary

Measure	Time frame
Matched population comparison of refractive and visual outcomes and patient satisfaction between ReLEx SMILE and PRK for the correction of low myopia (SEQ 4D)Timepoint: 6 months	—

Secondary

Measure	Time frame
Not ApplicableTimepoint: Not Applicable	—

Countries

India

Contacts

Public ContactDR SRI GANESH

NETHRADHAMA SUPERSPECIALITY EYE HOSPITAL

utsav_5093@yahoo.com09901903149

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026