To compare the safety and efficacy of amniotic membrane transplantation and cord blood serum in cases of acute chemical injury of the eye

A Prospective Randomized Controlled Clinical Trial to Compare the Safety and Efficacy of Topical Cord Blood Serum Drops and Amniotic Membrane Transplantation in Acute Chemical Injury

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/09/005067

Enrollment

Registered

2014-09-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Acute Ocular Chemical Injury Health Condition 2: T264- Burn of eye and adnexa, part unspecified

Interventions

Intervention1: Cord Blood Serum adjunctive to standard treatment: 15 patients of acute chemical injury treated with cord blood serum in adjunction to standard treatment Intervention2: Amniotic Membran

Eligibility

Inclusion criteria

Inclusion criteria: GRADE 3,4,5 CHEMICAL INJURY AS PER DUAS CLASSIFICATION PRESENTING WITH IN 3 WKS OF INJURIES

Exclusion criteria

Exclusion criteria: 1. GRADE 1,2,6 CHEMICAL INJURY AS PER DUAS CLASSIFICATION PRESENTING WITH IN 3 WKS OF INJURIES 2.IMPENDING PERFORATION OR PERFORATION AT PRESENTATION 3.NOT WILLING FOR PARTICIPATION OR FOLLOW UP

Design outcomes

Primary

Measure	Time frame
1.VISUAL ACUITY 2.DUAS CLASSIFICATION 3.CORNEAL CLARITY 4.EPITHELIAL DEFECT 5.LIMBAL INVOLVEMENTTimepoint: 3 MONTHS	—

Secondary

Measure	Time frame
1.PAIN SCORE 2.TEAR FILM STATUS 3.INTRAOCULAR PRESSURE 4.OTHER COMPLICATIONSTimepoint: 3 MONTHS	—

Countries

India

Contacts

Public ContactDr Namrata Sharma

Dr.R.P.Centre for Ophthalmic SCIENCES, AIIMS

divyas865@gmail.com09868354999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026