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Clinical research a siddha drug in the treatment ofPaithiyavatha Suronitham(Advanced stage of Rheumatoid Arthritis)

PRE CLINICAL AND CLINICAL EVALUATION OF ARUMUGA CHENDURAM IN THE MANAGEMENT OF PAITHIYAVATHA SURONITHAM ( RHEUMATOID ARTHRITIS)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/09/005046
Enrollment
40
Registered
2014-09-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- PAITHIYAVATHASURONITHAM (ADVANCED STAGE OF RHEUMATOID ARTHRITIS)

Interventions

Intervention1: ARUMUGA CHENDURAM: 100mg of Arumugachenduram will be administered along with honey twice a day orally for a period of 60 days Intervention2: AYAKANTHA CHENDURAM: 100mg of Ayakanthachend

Sponsors

Ayothidoss pandithar hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Onset of arthritis after the age of 16 years. 2.Positive for rheumatoid factor(RF). 3.Anti-CCP. 4.Either an erythrocyte sedimentation rate(ESR) of greater than 30mm/hr(OR)C-reactive protein level greater than 1.0mg/dl. 5.Diagnosis of PaithiyavathaSuronitham, as defined by fulfilling at least more than two articular involvement.

Exclusion criteria

Exclusion criteria: 1.Diabetes mellitus 2.Hypo & Hyperthyroidism 3.Hypertension 4.Cardiac disease 5.Renal disease 6.Liver disorders 7.Neurological disorders 8.Pregnancy and lactation 9.History of alcohol or substance abuse 10.Active infection, or chronic or persistent infection that might worsen with immunosuppressive treatment (e.g., HIV, hepatitis B virus, hepatitis C virus, tuberculosis [TB])

Design outcomes

Primary

MeasureTime frame
Pain measured by Visual analogue scaleTimepoint: Before Treatment (0th day) and After Treatment(60th day)

Secondary

MeasureTime frame
: Improving the other manifestations such as duration of morning stiffness (in minutes), Onset of fatigue (in minutes) after walking, Ritchies articular index for pain joints at each visit. â?¢ Hb, CRP, RF, and ESR under normal limits after completion of study Timepoint: Before treatment and After treatment

Countries

India

Contacts

Public ContactRAMAMURTHY

NATIONAL INSTITUTE OF SIDDHA

dr.kmvm@gmail.com9444979034

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026