Health Condition 1: null- PAITHIYAVATHASURONITHAM (ADVANCED STAGE OF RHEUMATOID ARTHRITIS)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Onset of arthritis after the age of 16 years. 2.Positive for rheumatoid factor(RF). 3.Anti-CCP. 4.Either an erythrocyte sedimentation rate(ESR) of greater than 30mm/hr(OR)C-reactive protein level greater than 1.0mg/dl. 5.Diagnosis of PaithiyavathaSuronitham, as defined by fulfilling at least more than two articular involvement.
Exclusion criteria
Exclusion criteria: 1.Diabetes mellitus 2.Hypo & Hyperthyroidism 3.Hypertension 4.Cardiac disease 5.Renal disease 6.Liver disorders 7.Neurological disorders 8.Pregnancy and lactation 9.History of alcohol or substance abuse 10.Active infection, or chronic or persistent infection that might worsen with immunosuppressive treatment (e.g., HIV, hepatitis B virus, hepatitis C virus, tuberculosis [TB])
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain measured by Visual analogue scaleTimepoint: Before Treatment (0th day) and After Treatment(60th day) | — |
Secondary
| Measure | Time frame |
|---|---|
| : Improving the other manifestations such as duration of morning stiffness (in minutes), Onset of fatigue (in minutes) after walking, Ritchies articular index for pain joints at each visit. â?¢ Hb, CRP, RF, and ESR under normal limits after completion of study Timepoint: Before treatment and After treatment | — |
Countries
India
Contacts
NATIONAL INSTITUTE OF SIDDHA