Health Condition 1: null- Localized epidermal dermatophytosis (epidermomycosis)
Conditions
Interventions
Intervention1: Sertaconazole (2%) cream: Sertaconazole (2%) cream to be applied locally once daily for 4 weeks
Control Intervention1: Terbinafine (1%) cream: Terbinafine (1%) cream to be applied local
Sponsors
R G Kar Medical College and Hospital Kolkata
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18-65 years 2. Patients of both sexes 3. Patients capable of giving informed consent 4. Patients with localized epidermal dermatophytosis confirmed by presence of fungal hyphae in KOH (potassium hydroxide) preparation of skin scrapings from over the lesion at baseline visit
Exclusion criteria
Exclusion criteria: 1. Patients with underlying immunosuppression 2. Pregnant or lactating women 3. Secondarily infected or eczematized lesions 4. Lesions over multiple anatomical regions 5. Lesions with nail or scalp involvement 6. Patients who received any type of anti-fungal therapy within 30 days prior to baseline visit 7. Patients who applied any other topical agent over the lesions prior to baseline visit 8. Patients incapable of understanding the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. "Complete clinical cure" defined as complete absence of erythema, scaling and pruritus and overall global assessment. 2. "Mycological cure" defined as absence of fungal hyphae in KOH preparation of skin scrapings from over the lesion.Timepoint: 2 and 4 weeks after randomization | — |
Secondary
| Measure | Time frame |
|---|---|
| Local adverse effects such as dryness, irritation, eczema, tenderness.Timepoint: 2 and 4 weeks after randomization;Scores of erythema, pruritus, scalingTimepoint: baseline, 2 and 4 weeks after randomization | — |
Countries
India
Contacts
Public ContactDattatreyo Chatterjee
R G Kar Medical College and Hospital Kolkata
Outcome results
None listed