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Blood salvage and reducing patient blood loss in major orthopedic surgery

Acute Normovolemic Hemodilution in major orthopedic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/09/004996
Enrollment
20
Registered
2014-09-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing major orthopedic surgery ( Total hip replacement/ Total knee replacement )

Interventions

Intervention1: Intraoperative blood salvage: A calculated amount of blood will be withdrawn before start of surgery and after induction of anesthesia and 3 times ringer lactate will be infused to crea

Sponsors

Department of Transfusion Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA (American Society of Anaesthesiologists) physical status I / II who are to undergo major orthopedic surgery (total hip replacement, total knee replacement, fracture of hip). 2. Patients expected blood loss is greater than 750 ml but less than 1500 ml. 3. Pre operative haemoglobin is more than 12 g/dl.

Exclusion criteria

Exclusion criteria: 1. Patients with history of ischaemic heart disease. 2. Patients suffering from renal or hepatic insufficiency. 3. Patients currently on anticoagulant therapy. 4. Patients suffering from active systemic infections.

Design outcomes

Primary

MeasureTime frame
Efficacy of ANH in major orthopedic surgery.Timepoint: till discharge from hospital—

Secondary

MeasureTime frame
Effects on clinical outcome and hospital stayTimepoint: till discharge from hospital—

Countries

India

Contacts

Public ContactNaveen Bansal

Government Medical College and Hospital, Chandigarh

docvpsingh@yahoo.co.in9646121576

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026