None listed
Conditions
Interventions
Intervention1: Inactivated Poliovirus Vaccine: IPV given intramuscularly (0.5 ml) to children who are previously immunized with trivalent OPV
Control Intervention1: Inactivated Poliovirus Vaccine: IPV
Sponsors
Christian Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Healthy children who have received trivalent OPV vaccines in primary series
Exclusion criteria
Exclusion criteria: Child has a known digestive system defect. Child has history of chronic diarrhea (lasting more than 14 days). Child has major congenital anomalies. Child has known immunodeficiency Child has received a prior dose of IPV
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of vaccine virus (type 1 & 3) in stool sample following bivalent OPV (1 and 3) (bOPV) six months after a supplementary dose of IPV compared to those who did not receive a supplementary dose of IPVTimepoint: Seven days after a dose of bOPV given 6 months following a supplementary dose of IPV in arm 1 | — |
Secondary
| Measure | Time frame |
|---|---|
| Prevalence of vaccine virus (type 1 & 3) in stool sample following bivalent OPV (1 and 3) (bOPV) twelve months after a supplementary dose of IPV compared to those who did not receive a supplementary dose of IPVTimepoint: Seven days after a dose of bOPV given 12 months following a supplementary dose of IPV in arm 2 | — |
Countries
India
Contacts
Public ContactJacob John
Christian Medical College
Outcome results
None listed