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Comparative evaluation of solifenacin and darifenacin for prevention of catheter related bladder discomfort

An evaluation of the efficacy of solifenacin and darifenacin for prevention of catheter-related bladder discomfor: A prospective, randomized, placebo-controlled, double-blind study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/08/004934
Enrollment
90
Registered
2014-08-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA grade I or II patient, Non diabetic, Non hypertensive and require catheterization

Interventions

Intervention1: Darifenacin: Darifenacin 7.5 mg, orally 1 hour before the induction of anesthesia with sips of water Intervention2: Solifenacin: Solifenacin 5 mg,orally 1 hour before the induction of a

Sponsors

Apollo Hospitals Bilaspur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grade I and II, 2.Non hypertensive and non diabetic 3.Scheduled for surgery under general anesthesia requiring catheterization

Exclusion criteria

Exclusion criteria: 1.patients with known sensitivity to study drugs, 2.history of drug or alcohol abuse, 3.history of chronic pain or daily intake of analgesics, 4.pregnant or breast-feeding females, 5.uncontrolled medical disease (diabetes mellitus and hypertension) 6.impaired kidney or liver functions and 7.psychiatric patients

Design outcomes

Primary

MeasureTime frame
To study the effect of solifenacin and darifenacin for prevention of catheter-related bladder discomfortTimepoint: On arrival in the post anesthesia care unit (0 hr) and again at 1, 2, and 6 hr later.

Secondary

MeasureTime frame
Postoperative fentanyl requirement Timepoint: Within 6 hr after completion of surgery

Countries

India

Contacts

Public ContactDr Vinit Kumar Srivastava

Apollo Hospitals Bilaspur (C.G.) India

drvinit75@gmail.com9755557539

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026