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Condition of newborns of mothers with convulsions, mother being treated with a medication, magnesium sulphate

ASSESSMENT OF BLOOD MAGNESIUM LEVELS AND ITS OUTCOME IN NEONATES OF ECLAMPTIC MOTHERS TREATED WITH LOW DOSE MAGNESIUM SULPHATE REGIMEN

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2014/08/004892
Enrollment
100
Registered
2014-08-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Neonates of Eclamptic mothers

Interventions

Intervention1: Nil: The low - dose regimen consisted of the following: a loading dose of 3g of magnesium sulphate intravenously plus a 2.5g intramuscular injection in each buttock (for a total of 8g
and neonates (of these eclamptic mothers) are not administered any magnesium sulphate

Sponsors

BURDWAN MEDICAL COLLEGE BURDWAN
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Eclampsia was diagnosed if there was h/o generalized tonic clonic convulsions with or without elevated blood pressure and proteinuria (by dipstick method) in the absence of any underlying seizure disorders after 20 wks of gestational age. 2. All cases of antepartum, intrapartum eclampsia, presenting in obstetric emergency, labour rooms and/or wards who gave informed consent to participate in the study were included in the study. 3. Neonates (of eclamptic mothers), of gestational age > 28 wks, were included in the study.

Exclusion criteria

Exclusion criteria: Eclampsia patients who had renal failure, severe pulmonary oedema with respiratory failure, having received magnesium sulphate and/or other anticonvulsant before coming to our hospital, cerebrovascular accident and Disseminated Intravascular Coagulation (DIC) were excluded from the from the present study. Neonates (of eclamptic mothers), of gestational age < 28 wks were excluded from the present study.

Design outcomes

Primary

MeasureTime frame
Assessment of neonatal outcome in terms of Apgar score(5min), time to first stool ( or 24 hrs), time to first void ( or 48 hrs) , admission to NICU, no. of episodes of feeding intolerance (3 or 3), %age of neonates with respiratory depression, %age of neonates with hypotonia.Timepoint: Early neonatal period

Secondary

MeasureTime frame
Cord blood magnesium level & maternal blood magnesium level at the time of deliveryTimepoint: At the time of delivery

Countries

India

Contacts

Public ContactMONALISA DAS

BURDWAN MEDICAL COLLEGE, BURDWAN

drpatralekha31@yahoo.com9007561801

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026