Health Condition 1: null- Dog bites
Conditions
Interventions
Intervention1: Shortened Essen Regimen for rabies prophylaxis: Injecting 1 dose of intramuscular anti rabies vaccine on days 0, 3, 7 & 14 (shortened Essen Regimen)for patients, where dog is healthy &
Sponsors
KIMS Hpspital
Eligibility
Inclusion criteria
Inclusion criteria: Healthy subjects with Category III exposures. If female, not pregnant or lactating at the time of enrolment and not planning pregnancy during the entire study period of 6 months. Previously unvaccinated/unexposed person. Willing to sign Informed consent to take 4 doses of IM vaccination (days 0, 3, 7 and 14), even when the dog is healthy and alive after 10 days. Subjects available for minimum of 6 months follow-up. Subjects willing to give blood samples on 4 recommended days i.e., on days 0, 14, 90 and 180.
Exclusion criteria
Exclusion criteria: Re exposure cases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| safety and Immunogenicity of new shortened Essen intramuscular regimenTimepoint: safety and Immunogenicity of new shortened Essen intramuscular regimen at the end of 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Estimation of Rabies virus neutralizing antibodiesTimepoint: on Days 14, 90 & 365 | — |
Countries
India
Contacts
Public ContactDr Rupsa Banerjee
Kempegowda Institute of Medical Sciences
Outcome results
None listed