Role of zinc supplementation in newborns with bloodstream infection

Role of zinc supplementation on acute inflammatory response and outcome in neonatal sepsis - a randomized controlled trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/08/004866

Enrollment

Registered

2014-08-11

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Neonatal sepsis

Interventions

Intervention1: Zinc sulfate along with standard antibiotic treatment: Dose â?? 1.5mg/kg/BD Mode of administration - oral Till discharge from hospital Control Intervention1: Standard antibiotic treatme

Eligibility

Inclusion criteria

Inclusion criteria: 1. Gestational age >= 32weeks 2. Age 3. Babies on enteral feeds. 4. Clinically diagnosed sepsis with at least two screening tests positive such as mESR, CRP and band cell count or positive blood culture.

Exclusion criteria

Exclusion criteria: 1. Surgical conditions and major congenital malformations. 2. Apgar score 3. Neonates who are already on treatment for sepsis.

Design outcomes

Secondary

Measure	Time frame
1. Associated complications (DIC, shock) 2. Duration of hospital stay 3. Requirement of antibiotics Timepoint: 10 days	—

Primary

Measure	Time frame
1. Decrease in mortality 2. Decrease in serum calprotectin level 3. Reduced adverse effects of acute inflammatory response Timepoint: 10 days	—

Countries

India

Contacts

Public ContactDr Vishnu Bhat

JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH

drvishnubhat@yahoo.com9842351282

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026