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A study to determine the interrelationship between diabetes and gum disease

ROLE OF PERIODONTAL THERAPY IN GLYCEMIC CONTROL AND ITS RELATIONSHIP WITH THE INFLAMMATORY MARKER TNF-α IN TYPE 2 DIABETIC PATIENTS-A CLINICO-BIOCHEMICAL STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/08/004849
Enrollment
30
Registered
2014-08-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- PATIENTS SUFFERING FROM TYPE 2 DIABETES MELLITUS AND PERIODONTITIS

Interventions

Intervention1: Group A was the treatment group: 30 PATIENTS WHO REPORTED TO THE DIABETES CLINIC OF SCHOOL OF TROPICAL MEDICINE, KOLKATA AS WELL AS THE OPD OF DEPARTMENT OF PERIODONTICS, Dr R AHMED DEN
OTHERS WERE RANDOMLY ASSIGNED TO EITHER TREATMENT OR CONTROL GROUP. GROUP A WHICH RECEIVED TREATMENT WITH FULL MOUTH SCALING AND ROOT PLANING FOLLOWED BY SYSTEMIC DOXYCYCLINE (100 MG DAILY FOR 14 DAYS

Sponsors

Dr r AHMED DENTAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: •Patients > 30 years, both males and females. •Chronic generalized periodontitis patients •Patients diagnosed with type 2 diabetes mellitus (HbA1c 7-10%) •No major diabetic complications. •Patient willing to take part in the study and maintain appointment regularly

Exclusion criteria

Exclusion criteria: •Patients suffering from any other systemic diseases. •Present and past smokers. •Patients who have undergone periodontal treatment 6 months prior to the study. •Pregnant or lactating mothers. •Patients who have received any antibiotics for the last three months. •Less than 16 remaining natural teeth

Design outcomes

Primary

MeasureTime frame
STATISTICALLY SIGNIFICANT REDUCTION IN SERUM TNF-ALPHA AND GLYCATED HAEMOGLOBIN AFTER PERIODONTAL TREATMENTTimepoint: 3 MONTHS

Secondary

MeasureTime frame
statistically significant reduction in clinical periodontal parameters after treatment namely, probing pocket depth (PPD), clinical attachment level (CAL), gingival and plaque indexTimepoint: 3 months

Countries

India

Contacts

Public ContactDr MANOJ KUMAR

Dr R AHMED DENTAL COLLEGE AND HOSPITAL

pbandyopadhyay1234@gmail.com9938899188

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026