Health Condition 1: null- Children aged â?¤ 12 years with DKA admitted to Pediatric emergency
Conditions
Interventions
Intervention1: Low dose: insulin 0.05 unit/kg/hour infusion will be started till resolution of diabetic keatoacidosis
Control Intervention1: standard dose: insulin 0.1 unit/kg/hr infusion will be star
Sponsors
Pediatric Critical Care Units
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 200 mg/dL 2. venous pH 3. Associated glycosuria, ketonuria, and ketonemia)
Exclusion criteria
Exclusion criteria: 1. Children with DKA who already received insulin infusion outside irrespective of duration and dose. 2. Children with a septic shock (requiring >= 60 ml/kg fluid boluses and vasoactive therapy to maintain vitals parameters during initial resuscitation).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the time taken for resolution of DKA in children with DKA receiving low dose insulin infusion (0.05units/kg/hr) as compared to those receiving standard dose (0.1units/kg/hr).Timepoint: Till resolution of DKA | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Rate of fall in RBS till â?¤ 250mg/dl. 2.Incidence of hypoglycemia and hypokalemia. 3.Incidence of cerebral edema and / or worsening of cerebral edema.Timepoint: During PICU stay | — |
Countries
India
Contacts
Public ContactDr Ramesh Kumar R
JIPMER
Outcome results
None listed