Health Condition 1: null- Biopsy proven squamous carcinoma, adenocarcinoma or adeno-squamous carcinoma of cervix, FIGO stage IB- IV A undergoing chemoradiation.
Conditions
Interventions
Intervention1: Zinc supplementation 40mg/day starting from one week prior to treatment until completion of treatment.: Patients will be supplemented with zinc 40mg/day starting from one week prior to
Sponsors
PGIMER
Eligibility
Inclusion criteria
Inclusion criteria: • Biopsy proven cancer cervix stage IB- IIIB • Karnofsky Performance Status minimum 70 • Patient fit for concurrent chemotherapy • Patient informed consent
Exclusion criteria
Exclusion criteria: • KPS less than 60 • Other primary malignancies except carcinoma in situ of the cervix and basal cell carcinoma of the skin • Metastatic disease beyond para-aortic region (L1-L2) • Previous pelvic or abdominal radiotherapy • Previous total or partial hysterectomy • Combination of preoperative radiotherapy with surgery • Patients receiving BT only • Patients receiving EBRT only • Patients receiving neoadjuvant chemotherapy • Active infection or severe medical condition endangering treatment delivery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess acute gastro-intestinal toxicity during and at treatment completion. Timepoint: Weekly during radiation treatment. At completion of treatment(41/2 to 5 weeks from onset of radiotherapy) | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the Quality of life at treatment completion.Timepoint: At treatment completion | — |
Countries
India
Contacts
Public ContactDr Vijai Simha
Post Graduate Institute of Medical Education and Research, Chandigarh
Outcome results
None listed