Health Condition 1: null- Trauma or other surgery of upper limb
Conditions
Interventions
Intervention1: Midazolam hydrochloride: initial dose of 0.04mg/kg intravenously in 10ml of normal saline and infused over 10 minutes, followed by a maintenance infusion of 0.04mg/kg/hr. for 2 hours.
C
Sponsors
Indira Gandhi Institute of medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade 1 & 2 2, Patient scheduled for upper extremity surgery where supraclavicular brachial plexus block is indicated
Exclusion criteria
Exclusion criteria: 1. known contraindication to brachial plexus block (patient refusal, coagulopathy, local infection) 2. known allergy to bupivacaine, midazolam and dexmedetomidine 3. concommittant us of analgesics or sedatives 4. history of significant cardiovascular, respiratory, neurological, psychiatric, hepatic or renal disease 5. failed brachial plexus block
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. onset and duration of motor block in minutes 2. onset and duration of sensory block in minutesTimepoint: 0,5,10,15,30,45,60,90,120,150, 180,210,240,270,300,330,360,390,420,450,480,510,540,570,600 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. incidence of hypotension (Mean arterial pressure less than 20% of baseline value) 2. incidence of bradycardia (Heart rate less than 50 BPM)Timepoint: 0, 10,20,30,40,50,60,70,80,90,120,150 minutes 180,210,240,270,300,330,360,390,420,450,480,510,540,570,600 minutes | — |
Countries
India
Contacts
Public ContactGunjan Kumar
Department of Anaesthesia, IGIMS, Patna
Outcome results
None listed