Health Condition 1: null- Uccha Raktachapa (Hypertension)
Conditions
Interventions
Intervention1: Rudraksa Churna (A Classical Ayurvedic Herbal Formulation): Dose 2gm (4 cap of 500 mg each) twice daily
Dosage Form Churna in cap.form
Route of Administration Oral
Time of Administ
Sponsors
Central Council for Research in Ayurvedic Sciences CCRAS
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex aged 18 years to 50yrs. Diagnosed patients of essential hypertension with: S.B.P. 140 mm. Hg. to 160 mm Hg. D.B.P. 90 mm. Hg. to 99 mm. Hg Hypertension Stage â??1, as per JNC VII report, 2004) Willing and able to participate for 14 weeks
Exclusion criteria
Exclusion criteria: 1. Patients who have a past history of Atrial Fibrillation, Acute Coronary Syndrome, Myocardial Infarction, Stroke or Severe Arrhythmia in the last 6 months. 2. Symptomatic patients with clinical evidence of Heart failure. 3. Secondary hypertension. 4. Patients with concurrent serious Hepatic Dysfunction (defined as AST and/or ALT > 3 times of the upper normal limit) or Renal Dysfunction (defined as S. creatinine > 1.2mg/dl),uncontrolled Pulmonary Dysfunction (asthmatic and COPD patients) or other concurrent severe disease. 5. Patients with Diabetes Mellitus {B.S. (F) > 126 mg/dl and / or B.S. (2 hr. PP) >200 mg/dl} 6. Women who are pregnant or lactating. 7. Patients on steroids, oral contraceptive pills or estrogen replacement therapy. 8. Alcoholics and/or drug abusers. 9. Serum Triglycerides >250 mg/dl 10. Patients with evidence of malignancy 11. Patients suffering from major systemic illness necessitating long term drug treatment (Rheumatoid arthritis, Psycho-Neuro-Endocrinal disorders, etc.) 12. H/o hypersensitivity to any of the trial drugs or their ingredients. 13. Patients who have completed participation in any other clinical trial during the past six (06) months. 14. Any other condition which the Investigator thinks may jeopardize the study. 15 Diagnosed cases of coronary disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes from baseline measurements in mean sitting systolic blood pressure and mean sitting diastolic blood pressure.Timepoint: Changes from baseline measurements in mean sitting systolic blood pressure and mean sitting diastolic blood pressure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in the SF-36-Health Survey Score. Change in Hamilton Anxiety Rating Scale (HAM â?? A) Score. Timepoint: 14th day, 28th day, 42nd day, 56th day, 70th day and 84th day after 4 weeks of follow up study | — |
Countries
India
Contacts
Public ContactDr Subhash singh
M.S. Ayurveda Central Research Institute,
Outcome results
None listed