Health Condition 1: null- ASA I/II patients coming for laparoscopic cholecystectomy
Conditions
Interventions
Intervention1: Ropivacaine: Patients in group II will receive intraperitoneal nebulisation using 4ml of 0.75% ropivacaine (3mg) with 2ml of normal saline
Intervention2: Ropivacaine and Fentanyl co
Sponsors
The Director
Eligibility
Inclusion criteria
Inclusion criteria: After obtaining written informed consent, 75 ASA I/II patients of both sexes & in the age group of 18-60 years, scheduled to undergo laparoscopic cholecystectomy under general anaesthesia will be enrolled in the study.
Exclusion criteria
Exclusion criteria: Exclusion criteria will be patients with: - coexisting disease affecting clinical assessment - acute preoperative pain other than biliary colic - chronic pain treatment - history of substance abuse - psychiatric illness - opiate tolerance - hepatic / renal dysfunction - coagulopathies - pregnancy / lactating females - allergy to any of the drugs used in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome of this study will be the incidence of significant pain (dynamic VAS â?¥30 mm), requiring rescue analgesic, during the first 48 hours after an elective laparoscopic cholecystectomyTimepoint: at PACU admission, 2 h, 4 h, 8 h, 12 h, 24h and at 48 hour interval | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures will include postoperative pain intensity at rest and on movement, as measured by visual analogue scale (VAS) scores, presence of postoperative shoulder pain, total opioid consumption in the postoperative period, time to first request for rescue analgesic and side-effects, if any, with the use of study drugs.Timepoint: at PACU admission, 2 h, 4 h, 8 h, 12 h, 24h and at 48 hour interval | — |
Countries
India
Contacts
Public ContactNidhi Bhatia
PGIMER, Chandigarh, India
Outcome results
None listed