Comparison between Dexmedetomidine and Fentanyl for pain relief after abdominal surgeries.

COMPARISON OF ANALGESIC EFFICACY OF DEXMEDETOMIDINE VERSUS FENTANYL AS AN ADJUNCT TO THORACIC EPIDURAL WITH BUPIVACAINE IN PATIENTS UNDERGOING UPPER ABDOMINAL SURGERY

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/08/004806

Enrollment

Registered

2014-08-01

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- scheduled for hepaticojejunostomy

Interventions

Intervention1: dexmedetomidine: 50 mics with 10 ml of 0.125% bupivacaine in thoracic epidural,intraoperatively.post-operatively 1 mics/ml dexmedetomidine with 0.125% bupivacaine-3ml bolus via PCEA pum

Eligibility

Inclusion criteria

Inclusion criteria: ASA Class I and II, undergoing elective hepaticojejunostomy

Exclusion criteria

Exclusion criteria: • BMI >35 kg/sq metre • Renal or hepatic dysfunction • Known cardiovascular disorder • Patients on beta-blockers, on long term treatment of antipsychotic drugs • Known allergy or senstivity to dexmedetomidine, bupivacaine or fentanyl • Contraindication to insertion of epidural catheter (local infection, spine deformities etc.) • Alcohol abuse, heavy smoking • Inability to use PCEA device

Design outcomes

Primary

Measure	Time frame
postoperative pain and analgesic requirementsTimepoint: 24 hours postoperatively	—

Secondary

Measure	Time frame
intraoperative analgesia and hemodynamic parametersTimepoint: assessed every 5 min after start of epidural infusion for 30 min ,every 15 min till end of surgery.	—

Countries

India

Contacts

Public ContactShweta Nandkumar Pokale

Postgraduate Institute Of Medical Education And Research

bhartineerja@yahoo.com9914209527

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026