To Study the effect of fluid challenge in patients with decompensated shock using advanced dynamic preload indices (SVV) in comparison to static preload indices (CVP)

The Comparison of Stroke Volume Variation with standard Hemodynamic measurements in predicting fluid responsiveness in septic patients with acute circulatory failure

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/07/004790

Enrollment

Registered

2014-07-31

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- critically ill patients with sepsis

Interventions

Intervention1: colloid ( hydroxyethyl starch ) 500 ml over 30 minutes: HES 6% (130/0.4) Control Intervention1: Stroke Volume Variation: A dynamic preload index measured using flotrac vigeleo Control I

Eligibility

Inclusion criteria

Inclusion criteria: patients with acute circulatory failure systolic blood pressure instrumentation with radial arteryor femoral arteryand central venous catheters and relative hemodynamic stability

Exclusion criteria

Exclusion criteria: patients with atrial fibrillation,severe arrythmias,pacemakers,need for mechanical cardiac support hypoxemia Pao2/Fio2 CVP > 12 PEEP >8

Design outcomes

Secondary

Measure	Time frame
improvement in hemodynamicsTimepoint: after half an hour of fluid challenge	—

Primary

Measure	Time frame
Decrease in Stroke volume variation and increase in cardiac indexTimepoint: After half an hour of fluid challenge.	—

Countries

India

Contacts

Public ContactSatyen Parida

JIPMER

jipmersatyen@gmail.com9940973502

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026