Health Condition 1: null- elective surgery for carcinoma pancrease, carcinoma common bile duct, carcinoma breast, gallbladder stone under general anesthesia, who will be catheterized after induction
Conditions
Interventions
Intervention1: Duloxetine 60mg tablet: Duloxetine 60mg will be given orally 2 hrs before the induction of anesthesia with sips of water
Control Intervention1: Placebo tablet, Aciloc (Ranitidine)75mg:
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adult patients (18 â?? 60 yr) with an ASA I and II 2.Of either sex, 3.All patients undergoing elective surgery under general anesthesia, who will be catheterized after induction,
Exclusion criteria
Exclusion criteria: 1.Patients with a history of bladder out�ow obstruction, 2.transurethral resection of prostate for benign prostate hyperplasia, 3.elderly patients (age .60 yr), 4.overactive bladder (frequency: more than three times in the night or more than eight times in 24 h) 5.End-stage renal disease (urine output ,500 ml per 24 h), 6.morbid obesity, 7.disturbance of central nervous system, 8.chemical substance abuse, 9.chronic pain, 10.Chronic analgesic usage. 11.cardiovascular, and hepatic or any psychiatric disease 12.Pregnancy and lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incedence and severity of catheter related bladder discomfortTimepoint: 0hr,1hr.2hrs,6hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| side effectsTimepoint: at the end of study | — |
Countries
India
Contacts
Public ContactDr Ghanshyam Yadav
Institute of Medical Sciences, Banaras Hindu University, Varanasi
Outcome results
None listed