A clinical trial to understand the effects of concurrently prescribed anticonvulsant mood stabilizer medications on the efficacy , cognitive adverse effects and brain electrical changes with electroconvulsive therapy

Concurrent Anticonvulsants in Bitemporal ECT : Seizure and Clinical Effects

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/07/004778

Enrollment

Registered

2014-07-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Bipolar Affective Disorders

Interventions

Intervention1: Full dose of anticonvulsant group, half dose of anticonvulsant group and stopped groups.: One arm having patients on full dose of anticonvulsant mood stabilizer , one arm with patients

Eligibility

Inclusion criteria

Inclusion criteria: 1. Referred by treating team for ECT and on anticonvulsants for reasons other than epilepsy. 2. Either Sex 3. Age 18 to 60 years 4. Informed consent for study

Exclusion criteria

Exclusion criteria: 1. Mental retardation (clinical examination) 2. Organic brain disease (by history and clinical examination)

Design outcomes

Primary

Measure	Time frame
Clinical Global Impression (severity) â?? maximum score 7Timepoint: On the day after the third, sixth and last ECT(electroconvulsive therapy) sessions	—

Secondary

Measure	Time frame
YMRS(Young Mania Rating Scale), HDRS(Hamilton Depression Rating Scale), PGI(Gognitive tests)Timepoint: Measured at the end of first and second weeks and before discharge.	—

Countries

India

Contacts

Public ContactDr Jagadisha Thirthalli

NIMHANS

jagatth@yahoo.com08026995350

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026