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Comparison of intravenous dexmedetomidine and midazolam in patients undergoing monitored anaesthesia care during cataract surgery

A comparative evaluation of intravenous dexmedetomidine and midazolam in patients undergoing monitored anaesthesia care during cataract surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/07/004769
Enrollment
60
Registered
2014-07-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients who are ASA grade 1 to 3 from 18 yrs to 80yrs and suffering from cataract of either eye

Interventions

Intervention1: Intravenous Dexmedetomidine : Mode of administration - intravenous. Its is a sedative and analgesic agent devoid of respiratory depressant properties with a short half life of 2 hours .

Sponsors

Government medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients of either sex 2) ASA grade 1 to 3 3) Age group of 18 to 80 years scheduled for elective cataract surgery

Exclusion criteria

Exclusion criteria: Patients with 1. history of chronic use of sedatives 2. history of alcohol abuse 3. second and third degree heart block , 4. significant cardio respiratory illness 5. history of sleep apnea 6. patients with BMI > 30

Design outcomes

Primary

MeasureTime frame
To compare and evaluate the effect of lower loading doses of dexmedetomidine sedation with those of midazolam sedation in patients undergoing cataract surgery under peribulbar anaesthesiaTimepoint: baseline , 5 min , 10 min , immediately after block , 5 min after , 10 min after , 15 min after ,20 min after. postoperatively 5 ,10, 15, 30 and 45 minutes

Secondary

MeasureTime frame
Comparison of hemodynamic parameters , sedation scores and post operative discharge criteriaTimepoint: baseline , 5 min , 10 min , immediately after block , 5 min after , 10 min after , 15 min after ,20 min after. postoperatively 5 ,10, 15, 30 and 45 minutes

Countries

India

Contacts

Public ContactDr Deepak Thapa

Govt medical college and hospital chandigarh

neetika_sahai@yahoo.com9999496559

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026