FindTrial
Sign In

Effect of oxygen during planned and emergency cesaraen section using spinal block on mother and new born baby

To evaluate effect of oxygen inhalation on maternal and fetal free radical activity during elective and emergency cesarean section under regional anesthesia - None

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/07/004759
Enrollment
120
Registered
2014-07-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O369- Maternal care for fetal problem, unspecified Health Condition 2: null- Pregnant women

Interventions

Intervention1: Oxygen 50 % : 50% oxygen through venture mask at 12.0 L/min from start of spinal block till the delivery of the fetus Control Intervention1: Oxygen 21 %: 21% oxygen through venture mas

Sponsors

INDIAN COUNCIL OF MEDICAL RESEARCH
Lead Sponsor
Government Medical College and Hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) grade I and II Age >18 years Single gestation Parturient requiring cesarean delivery for -fetal tachycardia 161-180 bpm ,fetal bradycardia 100-109 bpm, variability (bpm)

Exclusion criteria

Exclusion criteria: Patient refusal Fetal causes-Prematurity, any known fetal abnormality Any contraindication to regional anesthesia Body mass index >45 kg/M2 Parturient requiring cesarean delivery with indication of immediate threat to life of women or fetus with no time for placement of spinal anesthesia. Vasospastic arterial disease, previous arterial injury Thrombocytosis

Design outcomes

Primary

MeasureTime frame
Maternal and newborn plasma levels of Malondialdehyde (MDA) and total antioxidant statusTimepoint: Maternal plasma levels of Malondialdehyde (MDA) and total antioxidant status - arterial sample before spinal block to mother and then every 5 minutes till delivery of baby( means at 4-5 sample ) New born plasma levels of Malondialdehyde (MDA) and total antioxidant status - only one sample immediately after birth—

Secondary

MeasureTime frame
1. Maternal blood gas analysis 2. Fetal blood gas analysis 3.Haemodynamics 4.Maternal adverse effects- nausea ,vomiting etc 5.Newborn resuscitaion and follow up Timepoint: 1. baseline and then every 5 minutes till delivery of baby 2.only one sample at birth 3.baseline and then every 5 minutes till delivery of baby 4.During baseline till delivery of baby 5.At birth and at 24 hours—

Countries

India

Contacts

Public ContactVanita Ahuja

Government Medical College and Hospital

vanitaanupam@yahoo.co.in09646121649

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026