Health Condition 1: null- Forty children, aged 2-10 years, otherwise healthy with no other diseases admitted under the Department of Ophthalmology, PGIMER will be enrolled for the study after appropriate evaluation.
Conditions
Interventions
Intervention1: Dexmeditomidine drug: 2 different doses of dexmeditomidine i.e.0.15 microgm/Kg and 0.30 microgram/kg
Intervention2: Dexmeditomidine drug: 2 different doses of dexmeditomidine
Interventi
Sponsors
PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: . Forty children, aged 2-10 years, belonging to American Society of Anaesthesiologists (ASA) I - II admitted under the Department of Ophthalmology, PGIMER will be enrolled for the study after appropriate evaluation.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: .Lack of consent •Known adverse effects to dexmedetomidine •History of seizures or mental retardation •Developmental delay, or neurological or psychiatric illness that may associate with agitation (cerebral palsy, seizure, etc) • Known endocrine disease • A family history of malignant hyperthermia • Emergency procedure • Attention deficit hyperkinetic disorder • Psychiatric illness • History of paradoxical excitation with sedatives • History of previous episode of emergence delirium • preoperative EKG abnormality e.g. cardiovascular conduction disorder • Recent upper respiratory tract infections.(URTI). • Bleeding disorders / coagulation abnormalities. • Associated anomalies demanding deviation from standard anaesthetic protocol(Airway abnormalities precluding use of Laryngeal Mask Airway, tumor or infection of the orbit, compromised sclera, single eye vision, raised IOP)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effectiveness and safety of IV Dexmedetomidine (i.e. 0.15 µg/kg and 0.3µg/kg) for preventing desflurane induced emergence agitation in children undergoing cataract surgery under subtenon block.Timepoint: Different time intervals in Postoperative period | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the recovery profile with these two doses.Timepoint: Different time intervals in Postoperative period | — |
Countries
India
Contacts
Public ContactDr Sameer Sethi
Post Graduate Institute of Medical Education and Research(PGIMER)
Outcome results
None listed