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To evaluate decrease in consumption of inhalational anaesthetic agent, sevoflurane with use of a drug dexmedetomidine in laparoscopic cholecystectomy patients by maintaining adequate depth of anaesthesia

Sevoflurane sparing effect of dexemedetomidine with entropy monitoring in patients undergoing laparoscopic cholecystectomy; A randomized control trial.â?? - None

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/06/004687
Enrollment
100
Registered
2014-06-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients undergoing laparoscopic cholecystectomy

Interventions

Intervention1: Dexmedetomidine group: This group will receive 0.5µg per kg bolus of intravenous dexmedetomidine over 10 minutes, followed by infusion at the rate 0.5µg per kg per hour. Control Inter

Sponsors

GMCH Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age group of 18 to 60 years 2. American Society of Anaesthesiologists (ASA) status I and II

Exclusion criteria

Exclusion criteria: 1. Patients with significant cardio respiratory, hepatic or renal insufficiency 2. Patients on beta blockers , anticonvulsants, or any other centrally acting medications 3. Anticipated difficult airway 4. Pregnancy and lactation 5. Patient allergic to the study drug 6. Patients with known neurological disorder 7. Alcohol or substance abuse 8. Patients not willing for the study

Design outcomes

Primary

MeasureTime frame
To evaluate sevoflurane sparing effect of dexmedetomidine in patients scheduled for laparoscopic cholecystectomy under general anaesthesia. Timepoint: Every minute during surgery—

Secondary

MeasureTime frame
hemodynamic parameters and post operative recoveryTimepoint: Every 5 minutes during surgery and at time of shifting patient from PACU to ward—

Countries

India

Contacts

Public ContactPreeti Sharma

GMCH Chandigarh

dr_sgombar@rediffmail.com9646121520

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026