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A trial to compare two different drugs for spinal anaesthesia to prolong duration of analgesia during cesarean section

A randomized controlled trial to compare the effect of addition of fentanyl sulphate and magnesium sulphate as an adjunct to bupivacaine in spinal anesthesia during cesarean section on post operative analgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/06/004680
Enrollment
90
Registered
2014-06-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- women for cesarean section

Interventions

Intervention1: Women randomized to this group will receive hyperbaric bupivacaine with magnesium sulphate .: Women randomized to this group will receive 8 mg (1.6 ml) of 0.5% hyperbaric bupivacaine wi

Sponsors

Govt of Himachal Pradesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Singleton pregnancy • Woman for cesarean section as per obstetrical indication • Period of gestation between 36 to 41 weeks

Exclusion criteria

Exclusion criteria: • American society of Anesthesiologist grade >II • Renal or hepatic impairment • Thrombocytopenia • HELLP syndrome • Patient on magnesium therapy • Acute fetal distress • Contraindications to spinal anesthesia • Morbid Obesity (BMI > 38 kg/m 2) • Sensitivity to local anesthetic drugs

Design outcomes

Primary

MeasureTime frame
The primary outcome will be the duration of spinal anesthesia in the study groups.Timepoint: six months

Secondary

MeasureTime frame
â?¢ Time taken for onset of sensory block â?¢ Time taken for onset of motor block â?¢ Time taken to achieve maximal sensory block â?¢ Duration of sensory block â?¢ Duration of motor block â?¢ Need and amount of rescue analgesia Timepoint: â?¢ Time taken for onset of sensory block â?¢ Time taken for onset of motor block â?¢ Time taken to achieve maximal sensory block â?¢ Duration of sensory block â?¢ Duration of motor block â?¢ Need and amount of rescue analgesia

Countries

India

Contacts

Public ContactChanderdeep Sharma

Dr RPGMC Kangra

cdsharma2006@gmail.com919218925471

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026