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use of dexmedetomidine with lignocaine for nerve block in forearm and hand surgeries for postoperative pain relief

COMPARATIVE STUDY OF DEXMEDETOMIDINE IN TWO DIFFERENT DOSES AS AN ADJUNCT TO LIGNOCAINE FOR AXILLARY BRACHIAL PLEXUS BLOCK A RANDOMISED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/06/004651
Enrollment
90
Registered
2014-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- healthy patients without any coexisting diseases

Interventions

Intervention1: dexmedetomidine (0.5microgram/kg): Group 2 - 23ml of 1.5% lignocaine + 2-3ml of dexmedetomidine (0.5microgram/kg)+ 4-5ml of normal saline Intervention2: dexmedetomidine (1 microgram/kg

Sponsors

Government of Himachal Pradesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA class I & II BMI 18.5 - 24.5 Undergoing surgeries of forearm and hand

Exclusion criteria

Exclusion criteria: Patients refusal for block Patients having bleeding disorders Local infection at the site where needle for block was to be inserted Allergic to study drugs Cardiac disease or abnormal ECG findings Patients in whom the block effect was partial and who required supplementary anesthesia

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the onset and duration of sensory and motor blockade with lignocaine alone and with dexmedetomidine in two different doses. To study and compare the duration of postoperative analgesia in three group of patients. Timepoint: Block was evaluated every 3 minutes up to 30 minutes after the injection of local anesthetic is completed. Further block assessment was done at hourly intervals up to 10 hours by a blinded anesthesiologist

Secondary

MeasureTime frame
To look for side effects of dexmedetomidine, if anyTimepoint: upto 10 hours by blinded anesthesiologist after the completion of block

Countries

India

Contacts

Public ContactDr Shelly Rana

Dr Rajendra Prasad Government Medical College

shelkbj@yahoo.com9418710783

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026